As part of a routine mission, a unit of National Guard soldiers stop at a New Mexico outpost in order to deliver equipment to a group of atomic scientists. When they arrive at the isolated research camp, however, they find it is mysteriously deserted. After spotting a distress signal in a distant mountain range, the team decide to embark on a search and rescue mission into the hills in order to locate the missing scientists. Little do they know that these are the very hills that the ill-fated Carter family once visited, and that a tribe of cannibalistic mutants lies in wait. And this time, there is an even larger force of evil at work that is intent on the soldiers’ very destruction: the worst of the worst - the family patriarch Papa Hades - plans to keep the women as breeders in order to ensure the survival of the mutant clan. Thus, the un-expecting group of soldiers must learn to band together against a foe that is intent on their very destruction.