In 2054, Paris is a labyrinth where all movement is monitored and recorded. Cut off from the world for its own protection, the city has nonetheless continued to expand. Now, 21st century skyscrapers overlay centuries-old architectural masterpieces. And below street level, a sophisticated network of streamlined plazas push up against the city's ancient, deteriorating tunnel systems. Casting a shadow over everything is the city's largest company, Avalon, which insinuates itself into every aspect of contemporary life to sell its primary export – eternal youth and beauty.

When 22-year-old Ilona (Romola Garai), one of Avalon's most promising scientists, is abruptly kidnapped, Avalon calls on Barthélémy Karas (Daniel Craig), a Paris cop with a hard-fought reputation for finding anyone, no matter what sacrifices he has to make along the way. As the trail gets hot, Karas senses he's not the only one looking for the beautiful enigma, and every witness he digs up seems to turn up dead.

To find Ilona and unlock the secrets of her disappearance, Karas must plunge deep into the parallel worlds of corporate espionage, organized crime and genetic research – where the truth imprisons whoever finds it first and miracles can be bought but at a great price.